Is chronic fatigue syndrome a sleep disorder?

Chronic fatigue syndrome (also known as myalgic encephalomyelitis) is a serious, long term condition characterised by extreme, incapacitating fatigue of at least 6 months duration with reduction in activity levels. Other symptoms might include post-exertional malaise lasting at least 24 hours, memory and concentration impairment, tender cervical or axillary lymphadenopathy, muscle pains, sore throat, joint […]

How credible are the proposed theories of Restless leg syndrome pathophysiology?

Restless leg syndrome is a chronic sensorimotor condition clinically defined and diagnosed by the presence of the following clinical criteria: [1] an urge to move legs, usually but not always associated with uncomfortable sensations, [2] rest worsening symptoms, [3] improvement of symptoms with gyration, movement or activity, [4] evening worsening of symptoms and [5] exclusion/denial […]

What is the most compelling mechanistic hypothesis for the occurrence of sleep walking?

Sleep walking or somnambulism is a sleep disorder characterised by ambulation during sleep, the persistence of sleep and an altered state of consciousness. It is also characterized by recurrent events of complex motor behaviour mostly occurring during the first third of the night where NREM sleep is predominant. Sleepwalkers are difficult to arouse, confused when […]